5-Nitrothiophene-2-carboxaldehyde → HCID 15410672, compound

HRID 726737Notes

Reaction equation

HRID 726737 reaction equation
[N+:1]([C:4]1[S:5][C:6]([CH:9]=O)=[CH:7][CH:8]=1)([O-:3])=[O:2].[F:11][C:12]([F:26])([F:25])[C:13]1[CH:18]=[CH:17][C:16]([S:19]([CH2:22][C:23]#[N:24])(=[O:21])=[O:20])=[CH:15][CH:14]=1>>[N+:1]([C:4]1[S:5][C:6](/[CH:9]=[C:22](/[S:19]([C:16]2[CH:15]=[CH:14][C:13]([C:12]([F:26])([F:11])[F:25])=[CH:18][CH:17]=2)(=[O:21])=[O:20])\[C:23]#[N:24])=[CH:7][CH:8]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 782815-Nitrothiophene-2-carboxaldehydeHCID 22000588[4-(Trifluoromethyl)benzene-1-sulfonyl]acetonitrile

Product 1

HCID 15410672HCID 15410672, compound

Procedure

Reaction of 2-nitrothiophen-5-carboxaldehyde and 4-trifluoromethylphenylsulfonylacetonitrile as in Example 1 gave (E)-3-(2-nitrothien-5-yl)-2-[4-(trifluoromethyl)phenylsulfonyl]acrylonitrile

Sources & evidence

ORD record
ord-1f3a0923d6d943c391ea32d5267726b1
Source dataset
uspto-grants-1998_01
Patent number
US05710173

Reaction notes

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