5-Nitrothiophene-2-carboxaldehyde → HCID 67581872, compound

HRID 726739Notes

Reaction equation

HRID 726739 reaction equation
[N+:1]([C:4]1[S:5][C:6]([CH:9]=O)=[CH:7][CH:8]=1)([O-:3])=[O:2].[F:11][C:12]([F:27])([F:26])[C:13]1[CH:14]=[C:15]([CH:23]=[CH:24][CH:25]=1)[CH2:16][S:17]([CH2:20][C:21]#[N:22])(=[O:19])=[O:18]>>[N+:1]([C:4]1[S:5][C:6](/[CH:9]=[C:20](/[S:17]([CH2:16][C:15]2[CH:23]=[CH:24][CH:25]=[C:13]([C:12]([F:27])([F:11])[F:26])[CH:14]=2)(=[O:19])=[O:18])\[C:21]#[N:22])=[CH:7][CH:8]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 782815-Nitrothiophene-2-carboxaldehydeHCID 27824342-(((3-(Trifluoromethyl)phenyl)methyl)sulfonyl)acetonitrile

Product 1

HCID 67581872HCID 67581872, compound

Procedure

Reaction of 2-nitrothiophen-5-carboxaldehyde and 3-trifluoromethylbenzylsulfonylacetonitrile as in Example 1 gave (E)-3-(2-nitrothien-5-yl)-2-[3-(trifluoromethyl)benzylsulfonyl]acrylonitrile

Sources & evidence

ORD record
ord-a399f01725ce42019e58b7e599deec41
Source dataset
uspto-grants-1998_01
Patent number
US05710173

Reaction notes

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