5-(Methylsulfanyl)thiophene-2-carbaldehyde → (E)-3-(2-methylmercaptothien-5-yl)-2-(thien-3-ylsulfonyl)acrylonitrile

HRID 726744Notes

Reaction equation

HRID 726744 reaction equation
[CH3:1][S:2][C:3]1[S:4][C:5]([CH:8]=O)=[CH:6][CH:7]=1.[S:10]1[CH:14]=[CH:13][C:12]([S:15]([CH2:18][C:19]#[N:20])(=[O:17])=[O:16])=[CH:11]1>>[CH3:1][S:2][C:3]1[S:4][C:5](/[CH:8]=[C:18](/[S:15]([C:12]2[CH:13]=[CH:14][S:10][CH:11]=2)(=[O:17])=[O:16])\[C:19]#[N:20])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 27369975-(Methylsulfanyl)thiophene-2-carbaldehydeHCID 27975192-(3-Thienylsulfonyl)acetonitrile

Product 1

HCID 67583517(E)-3-(2-methylmercaptothien-5-yl)-2-(thien-3-ylsulfonyl)acrylonitrile

Procedure

Reaction of 2-methylmercaptothiophen-5-carboxaldehyde and thien-3-ylsulfonylacetonitrile as in Example 1 gave (E)-3-(2-methylmercaptothien-5-yl)-2-(thien-3-ylsulfonyl)acrylonitrile

Sources & evidence

ORD record
ord-db99a9a57f824d788f72187bf9f5ef02
Source dataset
uspto-grants-1998_01
Patent number
US05710173

Reaction notes

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