HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenethylamine, (+)- → (R)-N-tert-butyl-3,3-dimethyl-2-(1-phenylethylimino)-butyramide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenethylamine, (+)- | HCID 643189 | — |
| Reactant | N-tert-Butyl-3,3-dimethyl-2-oxobutanamide | HCID 13355144 | — |
| Product | (R)-N-tert-butyl-3,3-dimethyl-2-(1-phenylethylimino)-butyramide | HCID 54448076 | 58.2% |
Reaction Steps
The procedure described under l) was carried out using 7.5 g of N-tert-butyl-3,3-dimethyl-2-oxo-butyramide and 15 g of (R)-1-phenylethylamine. There were isolated 6.8 g (58%) of (R)-N-tert-butyl-3,3-dimethyl-2-(1-phenylethylimino)-butyramide of boiling point 120° at 0.2 mbar. [α]=+40.9 (c=1.0, CHCl3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05710322 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-226a520cff7e4dce9cd8b645360985ee |
| Source note | uspto-grants-1998_01 |