HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 19707473, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 4-Phenoxybenzaldehyde | HCID 66139 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 19707473 | HCID 19707473 | — |
Reaction Steps
To a solution of 4-phenoxybenzaldehyde (704 mg, 3.56 mmol) in 15 mL of THF at -78° C. was added n-BuLi dropwise (3.73 mmol, 2.5M in hexane). After 24 hours, the reaction was poured into ethyl acetate and sat. aq. NaHCO3 solution, then washed with brine, dried (Na2SO4) and concentrated in vacuo to provide the crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05710171 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-0b16357306bf43d9bafdbd5422b3dd0e |
| Source note | uspto-grants-1998_01 |