2,4-Diamino-6-methyl-5-(2,3,5-trichlorophenyl)pyrimidine → 2,4-Diamino-5-(3,5-dichlorophenyl)-6-methylpyrimidine

HRID 727059Notes

Reaction equation

HRID 727059 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[C:13]([Cl:15])[CH:12]=[C:11]([Cl:16])[C:10]=2Cl)=[C:4]([CH3:18])[N:3]=1.ClC1C=C(CC#N)C=C(Cl)C=1>>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:10]=[C:11]([Cl:16])[CH:12]=[C:13]([Cl:15])[CH:14]=2)=[C:4]([CH3:18])[N:3]=1

Participants

3

Reactant 2

HCID 115512322,4-Diamino-6-methyl-5-(2,3,5-trichlorophenyl)pyrimidineHCID 126899782-(3,5-Dichlorophenyl)acetonitrile

Product 1

HCID 197050802,4-Diamino-5-(3,5-dichlorophenyl)-6-methylpyrimidine

Procedure

This compound was prepared in a manner analogous to the compound of Example 6 from 3,5-dichlorophenylacetonitrile (Aldrich). mp. 242°-244° C.

Sources & evidence

ORD record
ord-50c35bf3375541519bd15073b983b7cb
Source dataset
uspto-grants-1998_01
Patent number
US05712276

Reaction notes

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