HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2-iodobenzene → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2-iodobenzene | HCID 11993 | — |
| Reactant | 1,4-Dioxaspiro[4.5]decan-8-one | HCID 567415 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Hydrochloric Acid | HCID 313 | 10% |
| Product | 1-(2-Chlorophenyl)-1-cyclohexen-4-one | HCID 19705192 | — |
Reaction Steps
This compound is prepared in a manner analogous to that of Step D of Example 7, using 9.5 grams (0.040 mole) of 1-chloro-2-iodobenzene, 1.1 grams (0.044 mole) of magnesium turnings, 6.2 grams (0.040 mole) of 1,4-cyclohexanedione mono-ethylene ketal, and about 1 00 mL of aqueous 10% hydrochloric acid in about 95 mL of tetrahydrofuran, yielding 1-(2-chlorophenyl)-1-cyclohexen-4-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05712281 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-ca7d2fa62cc34f8899d956b2b416cfbb |
| Source note | uspto-grants-1998_01 |