(5-bromo-1-methyl-1H-pyrazol-4-yl)methanol → 5-bromo-1-methyl-1H-pyrazole-4-carbaldehyde

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Reaction Steps

(5-Bromo-1-methyl-1H-pyrazol-4-yl)methanol (C23) was converted to the product using a procedure analogous to that described for the synthesis of 1-(4-ethylphenyl)-1H-imidazole-5-carbaldehyde (C19) in Example 5, step 3. In this case, no chromatography was carried out. Yield: 1.46 g, 7.72 mmol, 92%. LCMS m/z 191.2 (M+1). 1H NMR (400 MHz, CDCl3) δ 3.93 (s, 3H), 7.96 (s, 1H), 9.76 (s, 1H).

Provenance & Evidence