HCID 19705230, compound → 2,4-Diamino-6-(2,3-dihydro-2,2-dimethylbenzofuran-5-yl)-5,6,7,8-tetrahydroquinazoline

HRID 727220Notes

Reaction equation

HRID 727220 reaction equation
[CH3:1][C:2]1([CH3:18])[CH2:6][C:5]2[CH:7]=[C:8]([CH:11]3[CH2:16][CH2:15][C:14](=O)[CH2:13][CH2:12]3)[CH:9]=[CH:10][C:4]=2[O:3]1.[C:19]([NH:21][C:22]([NH2:24])=[NH:23])#[N:20]>C(OCCOCCO)C>[NH2:24][C:22]1[N:21]=[C:19]([NH2:20])[C:15]2[CH2:16][CH:11]([C:8]3[CH:9]=[CH:10][C:4]4[O:3][C:2]([CH3:18])([CH3:1])[CH2:6][C:5]=4[CH:7]=3)[CH2:12][CH2:13][C:14]=2[N:23]=1

Participants

4

Reactant 2

HCID 19705230HCID 19705230, compoundHCID 178418324HCID 178418324, compound

Product 1

HCID 197052332,4-Diamino-6-(2,3-dihydro-2,2-dimethylbenzofuran-5-yl)-5,6,7,8-tetrahydroquinazoline

Reagents, catalysts & solvents 1

HCID 8146Diethylene Glycol Monoethyl EtherSolvent

Procedure

This compound is prepared in a manner analogous to that of Example 1, using 3.2 grams (0.013 mole) of 4-(2,3-dihydro-2,2-dimethylbenzofuran-5-yl)-1-cyclohexanone and 1.2 grams (0.014 mole) of cyanoguanidine in 2-(2-ethoxyethoxy)ethanol, yielding 2,4-diamino-6-(2,3-dihydro-2,2-dimethylbenzofuran-5-yl)-5,6,7,8-tetrahydroquinazoline.

Workup

  1. customThis compound is prepared in a manner analogous to that of Example 1

Sources & evidence

ORD record
ord-1c95cd68aaf94d3e92b6fca8503d4731
Source dataset
uspto-grants-1998_01
Patent number
US05712281

Reaction notes

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