HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 53801641, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | HCID 22101805 | HCID 22101805 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 53801641 | HCID 53801641 | — |
Reaction Steps
Acetyl chloride (0.6 ml) was added to a solution of 1-(4-methyl-5-thiazolyl)-1-phenylmethanol (800 mg) and pyridine (0.5 ml) in dichloromethane (30 ml) at 0° C. under an atmosphere of dry nitrogen. The mixture was allowed to warm room temperature and was then stirred overnight. Evaporation and purification of the residue by flash chromatography gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05712299 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-c1a6e7265cc94e8597484d6dbc0ab980 |
| Source note | uspto-grants-1998_01 |