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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 727251Generated: October 31, 2026

Pyridine → HCID 53801641, compound

https://huagongshe.com/reaction/727251

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantAcetyl chlorideHCID 6367—
ReactantHCID 22101805HCID 22101805—
SolventDichloromethaneHCID 6344—
ProductHCID 53801641HCID 53801641—

Reaction Steps

Acetyl chloride (0.6 ml) was added to a solution of 1-(4-methyl-5-thiazolyl)-1-phenylmethanol (800 mg) and pyridine (0.5 ml) in dichloromethane (30 ml) at 0° C. under an atmosphere of dry nitrogen. The mixture was allowed to warm room temperature and was then stirred overnight. Evaporation and purification of the residue by flash chromatography gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05712299
Source datasetuspto-grants-1998_01
ORD IDord-c1a6e7265cc94e8597484d6dbc0ab980
Source noteuspto-grants-1998_01