4-Methyl-1,3-oxazole-5-carbaldehyde → 1-(2-Furyl)-1-(4-methyl-5-oxazolyl)methanol

HRID 727255Notes

Reaction equation

HRID 727255 reaction equation
[CH3:1][C:2]1[N:3]=[CH:4][O:5][C:6]=1[CH:7]=[O:8].[O:9]1[CH:13]=[CH:12][CH:11]=[C:10]1[Li]>>[O:9]1[CH:13]=[CH:12][CH:11]=[C:10]1[CH:7]([C:6]1[O:5][CH:4]=[N:3][C:2]=1[CH3:1])[OH:8]

Participants

3

Reactant 2

HCID 149205234-Methyl-1,3-oxazole-5-carbaldehydeHCID 178418296HCID 178418296, compound

Product 1

HCID 221018111-(2-Furyl)-1-(4-methyl-5-oxazolyl)methanol

Procedure

The title compound was prepared from 4-methyl-5-oxazolecarbaldehyde and 2-furyllithium using the method of Example 28. M.p. 52°-54° C.

Sources & evidence

ORD record
ord-dddb38681b654bb09cb9b55dc756ed55
Source dataset
uspto-grants-1998_01
Patent number
US05712299

Reaction notes

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