Methyl iodide → 131988-12-0

HRID 727282Notes

Reaction equation

HRID 727282 reaction equation
[CH3:1][I:2].[CH2:3]([O:5][C:6]1[C:7]([C:11]2[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=2)=[N:8][S:9][N:10]=1)[CH3:4]>CC(C)=O>[I-:2].[CH2:3]([O:5][C:6]1[C:7]([C:11]2[CH:12]=[N+:13]([CH3:1])[CH:14]=[CH:15][CH:16]=2)=[N:8][S:9][N:10]=1)[CH3:4]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 15180131Pyridine, 3-(4-ethoxy-1,2,5-thiadiazol-3-yl)- (9CI)

Product 1

HCID 15819042131988-12-0

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.3 ml, 5 mmol) and 3-(4-ethoxy-1,2,5-thiadiazol-3-yl)pyridine (520 mg, 2.5 mmol) in acetone (10 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.72 g (83%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.72 g (83%)

Sources & evidence

ORD record
ord-405aeb98a95b4a549f5b48a3ccee501f
Source dataset
uspto-grants-1998_01
Patent number
US05712297

Reaction notes

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