Methyl iodide → 3-(3-Pentyloxy-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

HRID 727290Notes

Reaction equation

HRID 727290 reaction equation
[CH3:1][I:2].[CH2:3]([O:8][C:9]1[C:10]([C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)=[N:11][S:12][N:13]=1)[CH2:4][CH2:5][CH2:6][CH3:7]>CC(C)=O>[I-:2].[CH2:3]([O:8][C:9]1[C:10]([C:14]2[CH:15]=[N+:16]([CH3:1])[CH:17]=[CH:18][CH:19]=2)=[N:11][S:12][N:13]=1)[CH2:4][CH2:5][CH2:6][CH3:7]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 151801343-(3-Pentyloxy-1,2,5-thiadiazol-4-yl)pyridine

Product 1

HCID 190755023-(3-Pentyloxy-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.3 ml, 5 mmol) and 3-(4-pentyloxy-1,2,5-thiadiazol-3-yl)pyridine (620 mg, 2.5 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.81 g (84%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.81 g (84%)

Sources & evidence

ORD record
ord-b526ed09643e43c69780818a1079c8b6
Source dataset
uspto-grants-1998_01
Patent number
US05712297

Reaction notes

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