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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 727293Generated: October 28, 2026

Isoamyl Alcohol → HCID 19075319, compound

https://huagongshe.com/reaction/727293

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoamyl AlcoholHCID 31260—
ReactantSodiumHCID 5360545—
Reactant3-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazoleHCID 10488164—
ProductHCID 19075319HCID 19075319—

Reaction Conditions

Temperature50 °C

Reaction Steps

To a solution of sodium (230 mg, 10 mmol) in isopentanol (20 ml) was added 3-(4-chloro-1,2,5-thiadiazol-3-yl)pyridine (490 mg, 2.5 mmol). The mixture was stirred at 50° C. for 2 h and evaporated. The residue was dissolved in water and extracted with ether. The combined organic phases were dried and evaporated to give the wanted compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05712297
Source datasetuspto-grants-1998_01
ORD IDord-8fdf3cb854ff4dd2b60cb463e732010d
Source noteuspto-grants-1998_01