Methyl iodide → 3-(4-Hexyloxy-1,2,5-thiadiazol-3-yl)-1-methylpyridine iodide

HRID 727296Notes

Reaction equation

HRID 727296 reaction equation
[CH3:1][I:2].[CH2:3]([O:9][C:10]1[C:11]([C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[N:12][S:13][N:14]=1)[CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]>CC(C)=O>[I-:2].[CH2:3]([O:9][C:10]1[C:11]([C:15]2[CH2:16][N:17]([CH3:1])[CH:18]=[CH:19][CH:20]=2)=[N:12][S:13][N:14]=1)[CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 151801353-(4-(Hexyloxy)-1,2,5-thiadiazol-3-yl)pyridine

Product 1

HCID 197053923-(4-Hexyloxy-1,2,5-thiadiazol-3-yl)-1-methylpyridine iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.5 ml, 7.5 mmol) and 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)pyridine (658 mg, 2.5 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.81 g (80%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.81 g (80%)

Sources & evidence

ORD record
ord-7b41fe46c1b7433583d59dbda891033f
Source dataset
uspto-grants-1998_01
Patent number
US05712297

Reaction notes

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