Methyl iodide → 3-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide

HRID 727305Notes

Reaction equation

HRID 727305 reaction equation
[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:4][S:5][N:6]=1.[CH3:13][I:14]>CC(C)=O>[I-:14].[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[N+:9]([CH3:13])[CH:10]=[CH:11][CH:12]=2)=[N:4][S:5][N:6]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 104881643-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazole

Product 1

HCID 190753343-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodideYield 100.1%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of 3-(4-chloro-1,2,5-thiadiazol-3-yl)pyridine (1.98 g, 10 mmol) and methyl iodide (4.25 g, 30 mmol) in acetone (10 ml) was stirred at room temperature for 16 h. The precipitate was collected by filtration to yield 3.40 g (100%) of the title compound.

Workup

  1. filtrationThe precipitate was collected by filtration

Sources & evidence

ORD record
ord-67d72ee930f548fda3245d1cec0d8a8f
Source dataset
uspto-grants-1998_01
Patent number
US05712297

Reaction notes

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