Potassium Acetate → HCID 18931681, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 8 g (20 mmol) of sodium 2-amino-5-bromo-3'-nitro[1,1'-biphenyl]-3-sulphonate, 7.6 g (120 mmol) of ammonium formate, 2.35 g (24 mmol) of potassium acetate and 1.38 g (1.2 mmol) of tetrakis(triphenylphosphine)palladium (0) in dimethylformamide is heated at 75° C. for 8 hours. The reaction medium is then concentrated under reduced pressure and the residue is purified by chromatography on an RP 18 column, eluting with a water/acetonitrile mixture (8:2). The product is recrystallized from an ethanol/ether mixture.

Provenance & Evidence