HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19705533, compound → HCID 19705481, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19705533 | HCID 19705533 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 19705481 | HCID 19705481 | 97.5% |
Reaction Steps
A mixture of tert-butyl α-azido-3-(2-methylpropyl)-2-oxo-1-(2-phenylethyl)-3-pyrrolidineacetate (159 mg, 0.397 mmol), palladium on carbon (10%, 40 mg) and EtOH (2.0 mL) is hydrogenated overnight at 30 psi. The mixture is filtered and concentrated to give 145 mg (97%) of the title compound as an oil:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05712300 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-6bb8fe20e64b444595ad2809a0486b1f |
| Source note | uspto-grants-1998_01 |