HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-(+)-1-Boc-3-aminopyrrolidine → HCID 88299764, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-(+)-1-Boc-3-aminopyrrolidine | HCID 854070 | — |
| Reactant | (2S,4S)-4-(4-methoxybenzyl)thio-1-(4-nitrobenzyloxycarbonyl)-L-proline | HCID 15297071 | — |
| Product | HCID 88299764 | HCID 88299764 | 18.2% |
Reaction Steps
Following a procedure similar to that described in Preparation 19, but using 6.4 g of (2S,4S)-4-(4-methoxybenzylthio)-1-(4-nitrobenzyloxycarbonyl)-2-pyrrolidinecarboxylic acid, 2.40 g of N,N'-carbonyldiimidazole and 2.7 g of (3R)-3-amino-1-t-butoxycarbonylpyrrolidine, 750 mg of the title compound were obtained as a powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05712267 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-96ca4c4ae05b4184a385d9d617ca0207 |
| Source note | uspto-grants-1998_01 |