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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 727709Generated: October 29, 2026

p-nitrobenzyl (1R,5R,6S)-2-(di-phenylphosphoryloxy)-6-[(R)-1-hydroxyethyl]-1-methyl-carbapen-2-em-3-carboxylate → HCID 22881556, compound

https://huagongshe.com/reaction/727709

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-nitrobenzyl (1R,5R,6S)-2-(di-phenylphosphoryloxy)-6-[(R)-1-hydroxyethyl]-1-methyl-carbapen-2-em-3-carboxylateHCID 15871605—
ReactantHCID 140386403HCID 140386403—
ProductHCID 22881556HCID 22881556—

Reaction Steps

A procedure similar to that described in Example 101 was repeated, but using 4-nitrobenzyl (1R,5R,6S)-2-(diphenylphosphoryloxy)-6-[(1R)-1-hydroxyethyl]-1-methyl-1-carbapen-2-em-3-carboxylate (prepared as described in Preparation 32) and (2S,4S)-4-mercapto-1-(4-nitrobenzyloxycarbonyl)-2-[1-(4-nitrobenzyloxycarbonylamidino)azetidin-3-ylcarbamoyl]pyrrolidine (prepared as described in Preparation 112) as starting materials, in relative proportions similar to those used in that Example, to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05712267
Source datasetuspto-grants-1998_01
ORD IDord-e34535edc3b34b6b9fcd369b68ddbb8d
Source noteuspto-grants-1998_01