Benzenesulfonyl chloride, 4-chloro-3-nitro- → HCID 14324551, compound

Participants

Reaction Conditions

Reaction Steps

1 l of dichloromethane was added to 800 g of 4-chloro-3-nitrobenzenesulfonyl chloride. The admixture was cooled to a temperature of 0° C. A mixture of 600 g of hexadecylamine, 251 ml of triethylamine, and 780 ml of dichloromethane was added dropwise to the solution in such a manner that the temperature thereof was kept at 20° to 30° C. After being allowed to react at room temperature for 20 hours, dichloromethane was removed from the reaction mixture under reduced pressure. The residue was dissolved in 3 l of methanol under heating. The solution was gradually cooled to room temperature where crystallization took place. 3 of methanol was then added to the solution. The solution was cooled with ice to induce crystallization. The crystals were then

Provenance & Evidence