Saccharin → 3-Butyl-1,2-benzisothiazole-1,1-dioxide

Participants

Reaction Steps

This material was prepared by adding 2 equivalents of butyllithium to saccharin in THF at -78° C., followed by aqueous workup at pH 9 as described in the literature by Abramovitch et al., J. Chem. Soc. Perkin I, 1974, 2589.

Provenance & Evidence