HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Cyclohexanedione → 3-(1,2,3,4-Tetrahydro-1-quinolinyl)-2-cyclohexen-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Cyclohexanedione | HCID 10434 | — |
| Reactant | 1,2,3,4-Tetrahydroquinoline | HCID 69460 | — |
| Product | 3-(1,2,3,4-Tetrahydro-1-quinolinyl)-2-cyclohexen-1-one | HCID 19825089 | 15.6% |
Reaction Steps
A mixture of 1,2,3,4-tetrahydroquinoline (5 g) and 1,3-cyclohexanedione (4.21 g) was heated at ca. 150° for 5 h. The cooled reaction mixture was purified by FCC eluting with ethyl acetate to give the title compound (1.33 g) as an oil, t.l.c. (ethyl acetate) Rf 0.34.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05045545 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-1460907208b4404892012a734759fd70 |
| Source note | uspto-grants-1991_09 |