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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 727830Generated: October 31, 2026

4-Chloro-N-methylbenzenamine → 4-[N-(4-chlorophenyl)-N-methylsulphamoyl]imidazole

https://huagongshe.com/reaction/727830

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-N-methylbenzenamineHCID 70272—
ReactantHCID 178527435HCID 178527435—
Product4-[N-(4-chlorophenyl)-N-methylsulphamoyl]imidazoleHCID 178482149—

Reaction Steps

Imidazole-4-sulphonyl chloride was reacted with 4-chloro-N-methylaniline to give 4-[N-(4-chlorophenyl)-N-methylsulphamoyl]imidazole, m.p. 217°-9°. This was then treated with dimethylsulphamoyl chloride in a similar manner to that described in Example 1, to give 1-dimethylsulphamoyl-4-[N-(4-chlorophenyl)-N-methylsulphamoyl]imidazole, m.p. 131.5°-132°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05045557
Source datasetuspto-grants-1991_09
ORD IDord-3e96b47044874731acf046e5f4959f64
Source noteuspto-grants-1991_09