Water → Phenol, 3-amino-, sodium salt

HRID 727963Notes

Reaction equation

HRID 727963 reaction equation
O.[NH2:2][C:3]1[CH:4]=[C:5]([OH:9])[CH:6]=[CH:7][CH:8]=1.[OH-].[Na+:11]>C1(C)C=CC=CC=1>[NH2:2][C:3]1[CH:4]=[C:5]([O-:9])[CH:6]=[CH:7][CH:8]=1.[Na+:11]

Participants

5

Reactant 3

HCID 962WaterHCID 115683-AminophenolHCID 14798Sodium Hydroxide

Product 1

HCID 23669774Phenol, 3-amino-, sodium salt

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Another three-necked flask equipped with a Dean-Stark water separator, condenser, nitrogen inlet and outlet, thermometer and a mechanical stirrer is charged with 261.91 grams (2.4 moles) of meta-aminophenol, 192 grams (2.4 moles) of 50% aqueous sodium hydroxide and 720 milliliters of toluene. The mixture is heated at 100°-140° C. for three hours to remove all of the water and toluene and provide sodium meta-aminophenolate.

Workup

  1. temperatureThe mixture is heated at 100°-140° C. for three hours
  2. customto remove all of the water and toluene

Sources & evidence

ORD record
ord-4b91ec1204774a37899bf64494c29e28
Source dataset
uspto-grants-1991_09
Patent number
US05045625

Reaction notes

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