1-Dodecanol → HCID 19824476, compound
Reaction equation
[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:8]([C:9](Cl)=[O:10])=[CH:7][CH:6]=1)(=[O:3])[CH3:2].[CH2:14]([OH:26])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>N1C=CC=CC=1>[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:8]([C:9]([O:26][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[O:10])=[CH:7][CH:6]=1)(=[O:3])[CH3:2]Participants
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
In 10 ml of pyridine was dissolved 2.0 g of 4-acetoxybenzoic acid chloride, and 2.4 g of dodecyl alcohol was added to the solution. Reaction was carried out at room temperature with stirring. The reaction mixture was treated by customary procedures to obtain 2.4 g of dodecyl 4-acetoxybenzoate. In the same manner as described in Referential Example 13, the acetoxy group was selectively isolated to quantitatively obtain dodecyl 4-hydroxybenzoate. This ester was dissolved in 20 ml of pyridine and a solution of 2.2 g of 3-chloro-4-benzyloxybenzoic acid chloride in 20 ml of pyridine was added to the above solution. The mixture was reacted at room temperature with stirring overnight and the reaction mixture was treated by customary procedures to obtain 3.3 g of 4'-dodecyloxycarbonylphenyl 3-chloro-4-benzyloxybenzoate. In the same manner as described in Referential Example 10, this ester was catalytically reduced to obtain 2.7 g of 4'-dodecyloxycarbonylphenyl 3-chloro-4-hydroxybenzoate.
Workup
- additionwas added to the solution
- customReaction
- customwas carried out at room temperature
- additionThe reaction mixture was treated by customary procedures
Sources & evidence
- ORD record
- ord-364bc63f61914de69f5c249dbd301dcc
- Source dataset
- uspto-grants-1991_09
- Patent number
- US05045228
Reaction notes
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