HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4-(2-Propoxybenzamido)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Amino-3-pyridinecarboxamide | HCID 13498082 | — |
| Reactant | 2-Propoxybenzoyl chloride | HCID 15921913 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 4-(2-Propoxybenzamido)nicotinamide | HCID 22462387 | — |
Reaction Steps
In a similar manner to Example 1 a) reaction of 2-propoxybenzoyl chloride (0.79 g), 4-aminonicotinamide (0.55 g) and triethylamine (0.40 g) in acetonitrile (12 ml) afforded a crude product which was recrystallised from ethanol-ether to afford 4-(2-propoxybenzamido)nicotinamide, 0.53 g, m.p. 164°-166° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05047404 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-04b45d3d1e4d46519d176e5c58b7f2e9 |
| Source note | uspto-grants-1991_09 |