Methanol → 1-(4-Chlorobenzyl)-3,3-dimethyl-2-methoxycarbonylcyclopent-1-ene

HRID 728049Notes

Reaction equation

[Cl:1][C:2]1[CH:19]=[CH:18][C:5]([CH2:6][C:7]2[CH:11]([C:12]([O:14][CH3:15])=[O:13])[C:10]([CH3:17])([CH3:16])[CH2:9][CH:8]=2)=[CH:4][CH:3]=1.CO.C[O-].[Na+]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][C:7]2[CH2:8][CH2:9][C:10]([CH3:17])([CH3:16])[C:11]=2[C:12]([O:14][CH3:15])=[O:13])=[CH:18][CH:19]=1

Participants

Reactant 3

HCID 887Methanol

HCID 10942334Sodium Methoxide

HCID 19783659HCID 19783659, compound

Product 1

HCID 118327721-(4-Chlorobenzyl)-3,3-dimethyl-2-methoxycarbonylcyclopent-1-ene

Procedure

The crude 2-(4-chlorobenzyl)-4,4-dimethyl-3- methoxycarbonylcyclopent-1-ene obtained in Example 7 was refluxed for 15 hours in methanol containing one equivalent of sodium methoxide to give 1-(4-chlorobenzyl)-3,3-dimethyl-2-methoxycarbonyl- cyclopent-1-ene as an oil.

Sources & evidence

ORD record: ord-8a6e3dc1d82943ba8c8e94addefe5796
Source dataset: uspto-grants-1991_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05047426

Reaction notes

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