反应详情

温度

100 °C

To 1,4-diaminobutane (84.6 g) cooled with ice, acrylonitrile (50.9 g) was added dropwise. After the addition had been completed, the reaction mixture was stirred for 20 minutes under ice cooling, at 40° C. for one hour and at 100° C. for three hours in this order. The resultant mixture was purified by distillation under reduced pressure to obtain as colorless oil 1-(N-2-cyanoethyl)amino-4-aminobutane (66 g).

1. additionwas added dropwise
2. additionAfter the addition
3. distillationThe resultant mixture was purified by distillation under reduced pressure