HCID 15171484, compound → HCID 15171488, compound

Participants

Reaction Steps

A mixture of 3-(4-hydroxy-3-nitrobenzyl)-2,7-dimethylimidazo[1,2-a]pyridine (2.2 g) in ethanol (100 ml) and tetrahydrofuran (50 ml) was hydrogenated over 10% palladium on carbon (0.7 g) under atmospheric pressure of hydrogen gas for 5 hours at ambient temperature. The catalyst was removed by filtration and filtrate was concentrated in vacuo and the precipitate was collected by filtration to give 3-(3-amino-4-hydroxybenzyl)-2,7-dimethylimidazo[1,2-a]pyridine (1.4 g).

Provenance & Evidence