4-Nitrobenzaldehyde → HCID 53945835, compound

Participants

Reaction Steps

A solution of 2-amino-4-methylpyrimidine (32.74 g) in acetic anhydride (150 ml) was refluxed for one hour under stirring. To the above solution was added 4-nitrobenzaldehyde (49.8 g) and the resultant mixture was refluxed for 7 hours under stirring. The reaction mixture was cooled and the precipitate was collected by filtlation. The residue was washed with diethyl ether to give 2-acetamido-4-[2-(4-nitrophenyl)vinyl]pyrimidine (72.7 g).

Provenance & Evidence