Water → HCID 178428001, compound

Participants

Reaction Steps

Potassium 6-[2-(3,7-dimethylimidazo[1,2-a]pyridin-2-yl)ethyl]-2-benzoxazolesulfonate (1.10 g) was added to a mixture of guanidine hydrochloride (257 mg) and potassium hydroxide (150 mg) in N,N-dimethylformamide (12 ml). After being stirred for 4 hours at ambient temperature, the reaction mixture was mixed with water (110 ml) and ethyl acetate (20 ml). The resulting precipitate was collected, washed with water and recrystallized from ethanol to give 6-[2-(3,7-dimethylimidazo[1,2-a]-pyridin-2-yl)ethyl]-2-guanidinobenzoxazole (0.31 g).

Provenance & Evidence