Hydrochloric Acid → HCID 54119335, compound

Participants

Reaction Steps

A mixture of 2-[2-(4-acetamido-3-nitrophenyl)vinyl]-7-methoxy-3-methylimidazo[1,2-a]pyridine (8.2 g) in ethanol (80 ml) and 6N-hydrochloric acid (80 ml) was refluxed for 4 hours and the mixture was cooled to ambient temperature. The isolated precipitate was collected by filtration. To a precipitate was added water, and a mixture was adjusted to pH 8 with saturated aqueous potassium carbonate. The precipitate was collected by filtration and dried to give 2-[2-(4-amino-3-nitrophenyl)vinyl]-7-methoxy-3-methylimidazo[1,2-a]pyridine (7.62 g).

Provenance & Evidence