Water → HCID 10466361, compound

HRID 728194Notes

Reaction equation

HRID 728194 reaction equation
[C:1](OC(=O)C)(=[O:3])[CH3:2].[NH2:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][C:17]2[O:18][CH:19]=[CH:20][CH:21]=2)=[CH:11][CH:10]=1.O>N1C=CC=CC=1>[C:1]([NH:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][C:17]2[O:18][CH:19]=[CH:20][CH:21]=2)=[CH:11][CH:10]=1)(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 962WaterHCID 7918Acetic AnhydrideHCID 10241559HCID 10241559, compound

Product 1

HCID 10466361HCID 10466361, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Acetic anhydride (0.28 ml) was added dropwise to a solution of 2-[2-(4-aminophenyl)ethyl]furan (0.50 g) in pyridine (5 ml) at ambient temperature with stirring. After being stirred for 1 hour, the mixture was poured into water (50 ml) and the resulting precipitate was collected by filtration to give 2-[2-(4-acetamidophenyl)ethyl]furan (0.58 g).

Workup

  1. stirringAfter being stirred for 1 hour
  2. filtrationthe resulting precipitate was collected by filtration

Sources & evidence

ORD record
ord-7efc36ed255c4a89bdb1d4d5157470d9
Source dataset
uspto-grants-1991_09
Patent number
US05047411

Reaction notes

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