HCID 67930855, compound → HCID 67930799, compound

Participants

Reaction Steps

A solution of 1,6-anhydro-4-O-benzyl-3-deoxy-2-O-methyl-β-D-ribo-hexopyranose (see Example 3(1)) (4.5 g) in ethanol (20 ml) was added to a suspension of 10% palladium on carbon (0.2 g) in ethanol (50 ml) and the resulting mixture was stirred in a hydrogen atmosphere until uptake of hydrogen had ceased (5 hours). Celite was added and the mixture was filtered through two layers of glass fibre filter paper. The filtrate was concentrated to give a quantitative yield of the title compound as a colourless syrup which crystallised spontaneously. Filtration with the aid of a little hexane gave 2.52 g (88% yield) of crystalline title compound, m.p. 67°-68° C.; [α]D -87.2°.

Provenance & Evidence