Toluene → HCID 70895768, compound

Participants

Reaction Steps

To a stirred solution of 3,7-dibromo-1-fluoro-10-Boc-phenothiazine (8) (290 mg, 0.6 mmol) in toluene (10 mL) Pd(dba)2 (17.3 mg, 0.03 mmol), BINAP (13.5 mg, 0.02 mmol), Cs2CO3 (390 mg, 1.2 mmol) and morpholine (70 mg, 0.8 mmol) were added. The mixture was refluxed for 24 h. After that reaction mixture was filtered, solvent was removed under vacuum. Product was used without additional purification.

Provenance & Evidence