Toluene → HCID 70895830, compound

Participants

Reaction Steps

To a stirred solution of 3-dimethylamino-1-fluoro-7-bromo-10-Boc-phenothiazine (14) (200 mg, 0.45 mmol) in toluene (10 mL) Pd(dba)2 (14.4 mg, 0.025 mmol), BINAP (10.9 mg, 0.018 mmol), Cs2CO3 (326 mg, 1.0 mmol) and morpholine (87 mg, 1.0 mmol) were added. The mixture was refluxed for 24 h. After that reaction mixture was filtered, solvent was removed under vacuum. Product was used without additional purification.

Provenance & Evidence