Toluene → HCID 70895826, compound

Participants

Reaction Steps

To a stirred solution of 3-(4-Boc-1,4-diazepan-1-yl)-1-fluoro-7-bromo-10-Boc-phenothiazine (1.1 g, 2.0 mmol) in toluene (10 mL) Pd2(dba)3 (46 mg, 0.05 mmol), BINAP (31 mg, 0.018 mmol), Cs2CO3 (652 mg, 2.0 mmol) and morpholine (348 mg, 4.0 mmol) were added. The mixture was refluxed for 24 h. After that reaction mixture was filtered, solvent was removed under vacuum. Product was used without additional purification.

Provenance & Evidence