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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 728433Generated: October 30, 2026

1-Methylimidazole → 2-methoxy-1-octadecylcarbamoylthio-3-(3-N-methylimidazoliniopropylsulfonylamino)propane iodide

https://huagongshe.com/reaction/728433

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylimidazoleHCID 1390—
Reactant3-(3-Iodopropylsulfonylamino)-2-methoxy-1-octadecylcarbamoylthiopropaneHCID 14835034—
Product2-methoxy-1-octadecylcarbamoylthio-3-(3-N-methylimidazoliniopropylsulfonylamino)propane iodideHCID 8674504791%

Reaction Steps

A solution of 100 mg of 3-(3-iodopropylsulfonylamino)-2-methoxy-1-octadecylcarbamoylthiopropane IIa6 in 0.3 ml of N-methylimidazole is stirred at 25° C. overnight. After the solvent is evaporated, the residue is washed with water to give 102 mg of 2-methoxy-1-octadecylcarbamoylthio-3-(3-N-methylimidazoliniopropylsulfonylamino)propane iodide Ia24 in 91% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05047540
Source datasetuspto-grants-1991_09
ORD IDord-e492ce78286f46ea9de8b9b548d3fe4e
Source noteuspto-grants-1991_09