2-Aminomethyl-2-hexadecylthiomethyltetrahydrofuran → 2-(3-Chloropropylsulfonylaminomethyl)-2-hexadecylthiomethyltetrahydrofuran

HRID 728437Notes

Reaction equation

HRID 728437 reaction equation
[NH2:1][CH2:2][C:3]1([CH2:8][S:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH2:7][CH2:6][CH2:5][O:4]1.[Cl:26][CH2:27][CH2:28][CH2:29][S:30](NCC(OC)CSCCCCCCCCCCCCCCCC)(=[O:32])=[O:31]>>[Cl:26][CH2:27][CH2:28][CH2:29][S:30]([NH:1][CH2:2][C:3]1([CH2:8][S:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH2:7][CH2:6][CH2:5][O:4]1)(=[O:32])=[O:31]

Participants

3

Reactant 2

HCID 148349962-Aminomethyl-2-hexadecylthiomethyltetrahydrofuranHCID 14835022HCID 14835022, compound

Product 1

HCID 148350352-(3-Chloropropylsulfonylaminomethyl)-2-hexadecylthiomethyltetrahydrofuran

Procedure

2-Aminomethyl-2-hexadecylthiomethyltetrahydrofuran IVb1 is allowed to react and worked by the same procedure as described in (4). m.p. 44.5° to 45.5° C. The summary of the experimental condition and the physical data of the prodcut are listed in the Table 7.

Workup

  1. customto react

Sources & evidence

ORD record
ord-0a42b265c8964cb28beecffe512e49c8
Source dataset
uspto-grants-1991_09
Patent number
US05047540

Reaction notes

Loading…