1-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropane → 2-Hexadecylthiomethyl-2-(iodopropylsulfonylmethyl)tetrahydrofuran

HRID 728438Notes

Reaction equation

HRID 728438 reaction equation
ClCCCS(N[CH2:9][C:10]1([CH2:15][S:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:14][CH2:13][CH2:12][O:11]1)(=O)=O.C(SCC(OC)CN[S:54]([CH2:57][CH2:58][CH2:59][I:60])(=[O:56])=[O:55])CCCCCCCCCCCCCCC>>[CH2:17]([S:16][CH2:15][C:10]1([CH2:9][S:54]([CH2:57][CH2:58][CH2:59][I:60])(=[O:56])=[O:55])[CH2:14][CH2:13][CH2:12][O:11]1)[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]

Participants

3

Reactant 2

HCID 148350231-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropaneHCID 148350352-(3-Chloropropylsulfonylaminomethyl)-2-hexadecylthiomethyltetrahydrofuran

Product 1

HCID 541923622-Hexadecylthiomethyl-2-(iodopropylsulfonylmethyl)tetrahydrofuran

Procedure

2-(3-Chloropropylsulfonylaminomethyl)-2-hexadecylthiomethyltetrahydrofuran IIIb1 is allowed to react and worked by the same procedure as described in (5). m.p. 36° to 37° C. The summary of the experimental condition and the physical data of the prodcut are listed in the Table 8.

Workup

  1. customto react

Sources & evidence

ORD record
ord-ec0054925ebe42bfb85a4fe163cef41c
Source dataset
uspto-grants-1991_09
Patent number
US05047540

Reaction notes

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