3-Hexadecylthio-2-tert-butoxycarbonylaminopropylamine → 2-Tert-butoxycarbonylamino-3-(3-chloropropylsulfonylamino)-1-hexadecylthiopropane

HRID 728450Notes

Reaction equation

HRID 728450 reaction equation
[CH2:1]([S:17][CH2:18][CH:19]([NH:22][C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])[CH2:20][NH2:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[Cl:30][CH2:31][CH2:32][CH2:33][S:34](NCC(OC)CSCCCCCCCCCCCCCCCC)(=[O:36])=[O:35]>>[C:26]([O:25][C:23]([NH:22][CH:19]([CH2:20][NH:21][S:34]([CH2:33][CH2:32][CH2:31][Cl:30])(=[O:36])=[O:35])[CH2:18][S:17][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])=[O:24])([CH3:28])([CH3:27])[CH3:29]

Participants

3

Reactant 2

HCID 148350033-Hexadecylthio-2-tert-butoxycarbonylaminopropylamineHCID 14835022HCID 14835022, compound

Product 1

HCID 148350422-Tert-butoxycarbonylamino-3-(3-chloropropylsulfonylamino)-1-hexadecylthiopropane

Procedure

3-Hexadecylthio-2-tert-butoxycarbonylaminopropylamine IVe4 is allowed to react and worked up by the same procedure as described in (4). m.p. 100.5°-101.5° C. The summary of the experimental condition and the physical data of the product are listed in Table 7.

Workup

  1. customto react

Sources & evidence

ORD record
ord-f3a953f982e247979cafcb53692ff890
Source dataset
uspto-grants-1991_09
Patent number
US05047540

Reaction notes

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