1-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropane → 2-Butoxycarbonylamino-3-(3-iodopropylsulfonylamino)-1-octadecylcarbamoyloxypropane

HRID 728452Notes

Reaction equation

HRID 728452 reaction equation
[CH2:1]([O:5][C:6]([NH:8][CH:9]([CH2:33][NH:34][S:35]([CH2:38][CH2:39][CH2:40]Cl)(=[O:37])=[O:36])[CH2:10][O:11][C:12](=[O:32])[NH:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[O:7])[CH2:2][CH2:3][CH3:4].C(SCC(OC)CNS(CCC[I:69])(=O)=O)CCCCCCCCCCCCCCC>>[CH2:1]([O:5][C:6]([NH:8][CH:9]([CH2:33][NH:34][S:35]([CH2:38][CH2:39][CH2:40][I:69])(=[O:37])=[O:36])[CH2:10][O:11][C:12](=[O:32])[NH:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 148350231-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropaneHCID 19884242HCID 19884242, compound

Product 1

HCID 198842212-Butoxycarbonylamino-3-(3-iodopropylsulfonylamino)-1-octadecylcarbamoyloxypropane

Procedure

2-Butoxycarbonylamino-3-(3-chloropropylsulfonylamino)-1-octadecylcarbamoyloxypropane IIIe2 is allowed to react and worked up by the same procedure as described in (5). m.p. 96°-98° C. The summary of the experimental condition and the physical data of the product are listed in Table 8.

Workup

  1. customto react

Sources & evidence

ORD record
ord-82cd53a1b4b8471ab4831f67dfbc954e
Source dataset
uspto-grants-1991_09
Patent number
US05047540

Reaction notes

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