1-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropane → 2-Acetamido-3-(3-iodopropylsulfonylamino)-1-octadecylcarbamoyloxypropane

HRID 728453Notes

Reaction equation

HRID 728453 reaction equation
[C:1]([NH:4][CH:5]([CH2:29][NH:30][S:31]([CH2:34][CH2:35][CH2:36]Cl)(=[O:33])=[O:32])[CH2:6][O:7][C:8](=[O:28])[NH:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])(=[O:3])[CH3:2].C(SCC(OC)CNS(CCC[I:65])(=O)=O)CCCCCCCCCCCCCCC>>[C:1]([NH:4][CH:5]([CH2:29][NH:30][S:31]([CH2:34][CH2:35][CH2:36][I:65])(=[O:33])=[O:32])[CH2:6][O:7][C:8](=[O:28])[NH:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 148350231-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropaneHCID 14835045HCID 14835045, compound

Product 1

HCID 148350522-Acetamido-3-(3-iodopropylsulfonylamino)-1-octadecylcarbamoyloxypropane

Procedure

2-acetamido-3-(3-chloropropylsulfonylamino)-1-octadecylcarbamoyloxypropane IIIg1 is allowed to react and worked up by the same procedure as described in (5). m.p. 101°-102° C. The summary of the experimental condition and the physical data of the product are listed in Table 8.

Workup

  1. customto react

Sources & evidence

ORD record
ord-3b1294d91ed34c808f86f9612c0110bd
Source dataset
uspto-grants-1991_09
Patent number
US05047540

Reaction notes

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