1-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropane → 2-Butoxycarbonylamino-1-hexadecylthio-3-(3-iodopropylsulfonylamino)propane

HRID 728456Notes

Reaction equation

HRID 728456 reaction equation
[CH2:1]([O:5][C:6]([NH:8][CH:9]([CH2:28][NH:29][S:30]([CH2:33][CH2:34][CH2:35]Cl)(=[O:32])=[O:31])[CH2:10][S:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])=[O:7])[CH2:2][CH2:3][CH3:4].C(SCC(OC)CNS(CCC[I:64])(=O)=O)CCCCCCCCCCCCCCC>>[CH2:1]([O:5][C:6]([NH:8][CH:9]([CH2:28][NH:29][S:30]([CH2:33][CH2:34][CH2:35][I:64])(=[O:32])=[O:31])[CH2:10][S:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 148350231-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropaneHCID 198842582-Butoxycarbonylamino-3-(3-chloropropylsulfonylamino)-1-hexadecylthiopropane

Product 1

HCID 198842472-Butoxycarbonylamino-1-hexadecylthio-3-(3-iodopropylsulfonylamino)propane

Procedure

2-Butoxycarbonylamino-3-(3-chloropropylsulfonylamino)-1-hexadecylthiopropane IIIe4 is allowed to react and worked up by the same procedure as described in (5). m.p. 82°-83° C. The summary of the experimental condition and the physical data of the product are listed in Table 8.

Workup

  1. customto react

Sources & evidence

ORD record
ord-c0883bf0e8d5499eb6c8358e660e0510
Source dataset
uspto-grants-1991_09
Patent number
US05047540

Reaction notes

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