HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid monohydrate → 3-hexadecylthio-2-(5-methyl-2H-tetrazol-2-yl)propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Reactant | 2-(5-methyl-2H-tetrazol-2-yl)-3-triphenylmethoxypropanol | HCID 14835099 | — |
| Reactant | 1-hexadecylthio-2-(5-methyl-2H-tetrazol-2-yl)-3-triphenylmethoxypropane | HCID 19884196 | — |
| Solvent | MeOH tetrahydrofuran | HCID 21899815 | — |
| Product | 3-hexadecylthio-2-(5-methyl-2H-tetrazol-2-yl)propanol | HCID 14834987 | — |
Reaction Steps
Using 10.2 g of crude 1-hexadecylthio-2-(5-methyl-2H-tetrazol-2-yl)-3-triphenylmethoxypropane 5h and 500 mg (2.6 mM) of p-toluene sulfonic acid monohydrate in 200 ml of methanol-tetrahydrofurane (1:1) mixture is converted to 3.17 g (49% from the compound 4h) of the title compound Vh1 by the same procedure as described in (81).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05047540 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-1fe82996e621479cb523335cf41ab9b6 |
| Source note | uspto-grants-1991_09 |