HRID728492

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCCCCCCCCCCCCCCCCNC(=O)OCC(CN=[N+]=[N-])CC(C)OC(=O)c1ccccc1

HCID19884213

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCCCNC(=O)OCC(CN)CC(C)OC(=O)c1ccccc1

HCID14835012

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

A suspension of 1.617 g (2.89 mM) of 1-azido-2-(2-benzoyloxypropan-1-yl)-3-octadecylcarbamoyloxypropane m7b and 170 mg of 10% palladium on charcoal in 150 ml of methanol is hydrogenated under hydrogen atmosphere for 1 hour. The mixture is filtered and the solvent of the filtrate is evaporated to obtained crude titled compound m8.

WORKUP

后处理

filtrationThe mixture is filtered
customthe solvent of the filtrate is evaporated

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4efd53d7d0604a0fa3195470cfcdd670
来源数据集: uspto-grants-1991_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05047540
来源说明: uspto-grants-1991_09

反应 SMILES

[N:1]([CH2:4][CH:5]([CH2:29][CH:30]([O:32][C:33](=[O:40])[C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)[CH3:31])[CH2:6][O:7][C:8](=[O:28])[NH:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])=[N+]=[N-]>[Pd].CO>[C:33]([O:32][CH:30]([CH3:31])[CH2:29][CH:5]([CH2:6][O:7][C:8](=[O:28])[NH:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH2:4][NH2:1])(=[O:40])[C:34]1[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1