1-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropane → 2-Cyanomethyl-3-hexadecyloxy-1-(3-iodopropylsulfonylamino)propane

HRID 728500Notes

Reaction equation

HRID 728500 reaction equation
Cl[CH2:2][CH2:3][CH2:4][S:5]([NH:8][CH2:9][CH:10]([CH2:29][C:30]#[N:31])[CH2:11][O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])(=[O:7])=[O:6].C(SCC(OC)CNS(CCC[I:59])(=O)=O)CCCCCCCCCCCCCCC>>[C:30]([CH2:29][CH:10]([CH2:11][O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH2:9][NH:8][S:5]([CH2:4][CH2:3][CH2:2][I:59])(=[O:7])=[O:6])#[N:31]

Participants

3

Reactant 2

HCID 148350231-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropaneHCID 148350841-(3-Chloropropylsulfonylamino)-2-cyanomethyl-3-hexadecyloxypropane

Product 1

HCID 148350852-Cyanomethyl-3-hexadecyloxy-1-(3-iodopropylsulfonylamino)propane

Procedure

1-(3-Chloropropylsulfonylamino)-2-cyanomethyl-3-hexadecyloxypropane IIIn1 is allowed to react by the same procedure as described in (5). The summary of the experimental condition and the physical data of the product are listed in Table 8.

Workup

  1. customto react by the same procedure

Sources & evidence

ORD record
ord-9e815042265547f49ef21af4b0053135
Source dataset
uspto-grants-1991_09
Patent number
US05047540

Reaction notes

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