HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-Cyanomethyl-3-octadecylcarbamoyloxypropanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-Cyanomethyl-3-hexadecyloxypropanol | HCID 14834994 | — |
| Reactant | 2-Cyanomethyl-3-octadecylcarbamoyloxypropyl benzoate | HCID 54117556 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Cyanomethyl-3-octadecylcarbamoyloxypropanol | HCID 14834995 | 81.3% |
Reaction Steps
A mixture of 1.49 g (2.96 mM) of 2-cyanomethyl-3-n-octadecylcarbamoyloxypropyl benzoate n5', 1.66 ml (3.32 mM) of 2N aqueous sodium hydroxide in 15 ml of methanol and 15 ml of tetrahydrofuran is allowed to react by the same procedure as described in (137) and 966 mg (76.8% yield) of the titled compound Vn2 is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05047540 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-9c494ecd3ab04e5282f6ce1367fbd713 |
| Source note | uspto-grants-1991_09 |