2-Cyanomethyl-3-octadecylcarbamoyloxypropylamine → 1-(3-Chloropropylsulfonylamino)-2-cyanomethyl-3-octadecylcarbamoyloxypropane

HRID 728505Notes

Reaction equation

HRID 728505 reaction equation
[C:1]([CH2:3][CH:4]([CH2:7][O:8][C:9](=[O:29])[NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH2:5][NH2:6])#[N:2].[Cl:30][CH2:31][CH2:32][CH2:33][S:34](NCC(OC)CSCCCCCCCCCCCCCCCC)(=[O:36])=[O:35]>>[Cl:30][CH2:31][CH2:32][CH2:33][S:34]([NH:6][CH2:5][CH:4]([CH2:3][C:1]#[N:2])[CH2:7][O:8][C:9](=[O:29])[NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])(=[O:36])=[O:35]

Participants

3

Reactant 2

HCID 148350142-Cyanomethyl-3-octadecylcarbamoyloxypropylamineHCID 14835022HCID 14835022, compound

Product 1

HCID 148350861-(3-Chloropropylsulfonylamino)-2-cyanomethyl-3-octadecylcarbamoyloxypropane

Procedure

The crude 2-cyanomethyl-3-n-octadecylcarbamoyloxypropylamine IVn2 which was prepared above is allowed to react by the same procedure as described in (4). The summary of the experimental condition and the physical data of the product are listed in Table 7.

Workup

  1. customto react by the same procedure

Sources & evidence

ORD record
ord-e5057ea414dc41f0bbc936e6bc84963f
Source dataset
uspto-grants-1991_09
Patent number
US05047540

Reaction notes

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